Sleeping up with shoulder pain, may be caused by the pillow, but also may be sleeping in the incorrect position of the shoulder, the shoulder muscles often force and lead to local spastic pain. The treatment methods are as follows: 1, you can give local hot compress method, you can use hot water bag, hot towel or salt bag external compress, each compress 20-30 minutes, you can compress twice a day, can promote local blood circulation, relieve local muscle spasm, so as to be able to relieve pain. 2, you can apply external swelling and pain relief, blood circulation and blood stasis ointment. 3, you can do some local physical therapy, such as infrared If the pain is strong, you can take oral non-steroidal anti-inflammatory drugs for pain relief and symptomatic treatment, commonly used are ibuprofen, nimesulide, celecoxib and other drugs. Among them, celecoxib has relatively small side effects on the gastrointestinal tract, and if you have stomach problems, you can take celecoxib.