Immunohistochemistry is done after prostate enlargement surgery for differential diagnosis with prostate cancer. Clinically, prostate cancer starts insidiously and clinical symptoms are not obvious, so perfect immunohistochemistry is also for differential diagnosis with prostate cancer to avoid misdiagnosis and missed diagnosis. If cancer is suggested, it is often necessary to further expand the scope of surgery and remove the surrounding lymph nodes, and at the same time, it is also necessary to determine whether there is any metastasis in other tissues and organs, to further evaluate the prognosis of the tumor and to guide the clinical screening of targeted therapies. If prostate enlargement surgery is needed, it should be carried out under regular hospitals. If prostate cancer is suspected, relevant examinations should be carried out under the guidance of doctors to make a clear diagnosis.