Eczema into hard bumps may be skin mossy lesions, or induced neurodermatitis, need to take medication, surgical treatment and other ways to address the specific causes. 1. Erythroderma: mainly manifested as skin lesions with infiltration, thickening and roughness, which some patients may mistake for hard bumps. Patients need to use topical hydrocortisone, dexamethasone and other glucocorticoid ointments, as well as tacrolimus, pimecrolimus and other immunomodulators under the guidance of the doctor, and may also need to apply zinc oxide paste as prescribed by the doctor. For patients with extensive and severe lesions, skin resurfacing should be considered. 2. Neurodermatitis: Typical symptoms are the gradual appearance of hard, shiny, corn-like papules, which may appear as hard bumps. Patients need to follow the doctor’s instructions for external use of compound flumethasone, prednisolone and other glucocorticoid ointment, severe lesions need to cooperate with the doctor in the local injection of tretinoin injection and other glucocorticosteroid drugs. Patients also need to follow the doctor’s instructions to apply glycerine lotion, 10% black bean distillate oil ointment and other anti-itching drugs. For patients with severe itching, oral antihistamines such as cetirizine and loratadine are required. In summary, when eczema becomes hard bumps, patients need to go to the hospital in time, clear specific reasons, with the doctor for standardized treatment.