Individuals with low platelets need to be evaluated to determine if they can receive the new crown vaccine after the cause has been identified and cannot be treated in the same way. If the cause is acute leukemia and the disease is in the acute phase, the new crown vaccine cannot be given. The causes of low platelets are divided into three categories (impaired production, excessive destruction or consumption, and abnormal distribution). 1. Disorders of platelet production, such as acute leukemia, aplastic anemia, megaloblastic anemia. These patients need to take immunosuppressive drugs for a long time, and the disease has not been effectively controlled, it is not recommended to receive the new crown vaccine for the time being. 2. Destroy or consume too much, such as malignant lymphoma, primary thrombocytopenic purpura. This kind of patients belong to the contraindication of the new crown vaccine, not recommended to vaccinate the new crown vaccine. 3. Distributional abnormalities such as cirrhosis, hypersplenism and other diseases. If the disease is mild and has been effectively controlled, these patients can be considered for vaccination with New Crown vaccine. However, some patients with severe and progressive diseases that have not been effectively controlled are not recommended to receive New Crown vaccine. Patients with low platelets are advised to identify the cause and exclude the corresponding contraindications before receiving the new crown vaccine, and are advised to consult a regular hospital and not to vaccinate blindly.