High pressure 180mmHg low pressure 120mmHg belongs to the third level of hypertension, need to go to the hospital in time for treatment, follow the doctor’s instructions to take amlodipine, enalapril, valsartan, metoprolol, hydrochlorothiazide and other drugs to reduce blood pressure. High pressure 180mmHg low pressure 120mmHg belongs to the third level of hypertension, at any time there is a risk of cerebral hemorrhage, cerebral infarction, myocardial infarction, etc., you need to immediately under the guidance of the doctor to use medication to reduce blood pressure smoothly. In addition to renin angiotensin-converting enzyme inhibitors and renin angiotensin receptor antagonists can not be used in combination, other drugs can be used in combination with two or three drugs to lower blood pressure, which amlodipine and other calcium antagonists can be used after the use of the ankle edema and other adverse reactions, hydrochlorothiazide and other diuretics used for a long time with the risk of hypokalemia. Beta-blockers such as metoprolol are suitable for patients with tachycardia, and are prohibited for patients with bradycardia and atrioventricular block; renin angiotensin receptor antagonists are prohibited for pregnant women and patients with bilateral renal artery stenosis; renin angiotensin-converting enzyme inhibitors, in addition to being contraindicated in pregnant women and patients with bilateral renal artery stenosis, can lead to adverse reactions such as dry cough. If the examination found that the high pressure 180mmHg low pressure 120mmHg, please immediately consult a doctor to follow the doctor’s instructions for treatment.