Taking amlodipine benzenesulfonate lower extremity swelling may be physiological causes, adverse drug reactions, heart failure and other reasons; different causes of different treatments. 1. Physiological reasons: such as high salt diet, female pregnancy will appear lower extremity swelling. The swelling of the lower limbs can be improved by dietary adjustment and less consumption of high-salt food. Pregnant women should avoid sitting and standing for a long time, and the swelling of the lower limbs will be relieved after pregnancy. 2. Adverse drug reactions: amlodipine benzenesulfonate is a calcium antagonist, which can cause vasodilation, resulting in blood stasis causing swelling of the lower extremities, should be under the guidance of specialists to reduce the dose of the drug or replace other antihypertensive drugs. 3. Heart failure: the heart pumping function is weakened, the ejection of blood is reduced, the ventricular cavity pressure increases, the lower extremity venous return obstacles lead to fluid retention, lower extremity edema; should be used in accordance with the doctor’s instructions to increase the cardiac output of cardiac drugs such as digoxin, spironolactone diuretic edema and other treatments. Amlodipine benzenesulfonate is suitable for hypertension and coronary artery disease, which may cause patients to experience dizziness, headache, edema and other adverse reactions, and is contraindicated in patients who are allergic to dihydropyridines or any of the ingredients in this product. Therefore, eating amlodipine benzenesulfonate lower extremity edema should be timely to the hospital, improve the examination, clear the cause of the disease and then give targeted treatment.