Cornea replacement generally refers to corneal transplantation, and the hazards of the surgery mainly include the risks that may occur during the operation and the complications that may occur after the operation, which may lead to blindness of the patient in serious cases. 1. Intraoperative risks: During corneal transplantation, patients may experience complications such as loss of anterior chamber or anterior chamber hemorrhage, or even severe iris detachment, resulting in failure of the surgery and significant visual impairment of the patient. 2. Postoperative complications: After corneal transplantation, immune rejection or bacterial or fungal infections of the patient’s cornea after transplantation may occur, leading to failure of the surgery, and the patient may suffer from vision loss, eye pain and other uncomfortable symptoms. After the surgery, patients may also experience complications such as cataract and secondary glaucoma, resulting in impaired vision or even blindness. It is recommended that patients undergoing corneal transplantation follow the doctor’s instructions for care, undergo regular checkups, and seek prompt medical attention when discomfort occurs.