Bone puncture, or bone marrow puncture, is a frequently used examination method in hematology, which can make a clear diagnosis of most hematologic diseases and evaluate the therapeutic effect of hematologic diseases, and there are usually no sequelae. The patient’s periosteum needs to be pierced when performing the bone marrow puncture. If the puncture is more traumatic or the anesthesia is not sufficient, bleeding and local pain may occur, and if the patient is more sensitive to pain, he or she will usually feel significant pain, and the pain will be aggravated when walking and last for a long time. Usually after a period of healing, it will gradually disappear, and patients need not worry too much. 2. Infection: If the disinfection is not complete when performing bone marrow puncture, and the whole process of aseptic operation is not achieved, or if the trauma is exposed to moisture prematurely after the operation, it may cause inflammation or abscess in the surrounding skin subcutaneous tissue and induce infection, which may lead to osteomyelitis in serious cases. Patients are advised to choose a regular hospital and a professional doctor for the surgery, keep the affected area dry after surgery, and avoid excessive exercise during the recovery period to help reduce the possibility of postoperative complications.