Bronchial thermoplasty significantly reduces the burden of disease treatment by significantly reducing acute exacerbations of asthma, reducing the frequency of hospitalizations and emergency room visits, significantly improving the level of asthma control, and improving quality of life. The longest follow-up period worldwide was nearly 10 years, with the largest sample reporting a mean follow-up period of 5 years. Patients treated in these studies experienced significant and sustained improvements in quality of life, with some patients experiencing reductions in medication and individual patients discontinuing asthma medications.