How high CA199 will generally be 9 months after cholangiocarcinoma surgery is not clear in clinic, if the patient’s treatment effect is better, CA199 will generally decrease or fall to normal range; if the patient’s treatment effect is not good, the value of CA199 may increase accordingly. CA199 is a tumor marker with normal value of <37.00u/ml.CA199 can be used to assist in the diagnosis of cholangiocarcinoma, and can also monitor the changes of cholangiocarcinoma after surgery, and sometimes can be used as an assessment of the therapeutic effect of cholangiocarcinoma. If bile duct cancer patients achieve better therapeutic effect 9 months after surgery, CA199 value may decrease or return to normal level; if the patient’s therapeutic effect is not good, or there is tumor recurrence and tumor metastasis after surgery, CA199 value may be larger than normal. Cholangiocarcinoma patients should also go to the hospital regularly for follow-up after surgery to check the recovery of their condition.