Pressing the leg with a pit may be a kidney problem, such as in nephrotic syndrome, acute and chronic glomerulonephritis, hypertensive nephropathy, diabetic nephropathy and other kidney diseases. It may not be a kidney problem, but can also be seen in heart failure, dilated cardiomyopathy and other heart diseases; liver cirrhosis, liver necrosis, liver cancer and other liver diseases; hypothyroidism and other endocrine system diseases. 1. Pressing the legs with pits may be a kidney problem, which can be seen in nephrotic syndrome, acute and chronic glomerulonephritis, hypertensive nephropathy, diabetic nephropathy, chronic renal failure, IgA nephropathy and other renal disorders, which can lead to lower limb edema. 2. It may not be a kidney problem, but also can be seen in heart disease such as heart failure, dilated cardiomyopathy, etc., cardiac insufficiency can lead to edema, edema parts of the lower limbs, gradually spread to the whole body. Liver diseases such as cirrhosis, hepatic necrosis, and hepatocellular carcinoma can lead to hypoproteinemia due to excessive protein synthesis or consumption. Endocrine system diseases such as hypothyroidism, antidiuretic hormone secretion syndrome, Cushing’s syndrome, aldosterone secretion disorder, etc. can also lead to lower limb edema. If you find lower limb edema, it is recommended that you consult a doctor in a timely manner and follow the doctor’s instructions to standardize the diagnosis and treatment.