Gallstones mostly refer to gallbladder stones, and intrahepatic bile duct stones are more serious compared to gallbladder stones. Because intrahepatic bile duct stones mostly refer to stones occurring in the bile ducts, they may cause different degrees of bile duct obstruction, thus obstructive jaundice and impairment of liver function. If the bile duct obstruction is longer, it may also cause acute obstructive purulent cholangitis, which may lead to infectious shock and require timely surgical treatment. In addition, because of long-term repeated inflammation stimulation, the affected liver may appear atrophy, liver and bile ducts are malignant. Gallbladder stones, on the other hand, are stones that occur in the gallbladder and are usually asymptomatic or have mild symptoms, such as pain and fullness in the right upper abdomen. Treatment is mainly based on surgical removal of the gallbladder, and the prognosis is good.