Patients with appendicitis who opt for a minimally invasive laparoscopic procedure with postoperative wound dehiscence are considered to have an obese patient, increased postoperative abdominal pressure, combined subcutaneous fat liquefaction, or incisional infection. In case of incisional dehiscence, the patient will experience significant incisional pain, fever, and even the appearance of exudate. This should be promptly opened and regular dressing changes should be performed to remove purulent secretions from the incision. Systematic anti-infective treatment with intravenous fluid supplementation is also required. Smaller and more frequent meals with light, easily digestible food should be given to avoid causing recurrent bloating that can affect the healing of the incision. After the oozing from the wound surface is significantly reduced and the blood tests are within the normal range, secondary suturing of the wound can be performed at a later date. For small incisions, secondary suturing can be performed under local anesthesia.