Patients can perform a self-examination based on specific signs of appendicitis, but this method is limited in that even if the signs are consistent with the symptoms of appendicitis, it does not necessarily indicate that the patient has appendicitis. Therefore, self-examination is only a preliminary method to determine whether appendicitis is present, and may be misdiagnosed or missed. It is recommended that patients go to the hospital and undergo relevant imaging and laparoscopic examinations to clarify whether they have the disease.1. Right lower abdominal pressure pain: Right lower abdominal pressure pain is a more common and important sign of acute appendicitis, and the pressure pain point is usually located at the McDonald’s point, and the body location is at the junction of the right anterior superior iliac spine and the middle and outer 1/3 of the umbilical cord, which can change with the variation of the appendix location, but is always in a fixed position. Early in the course of the disease, when the abdominal pain has not yet metastasized to the right lower abdomen, fixed pressure pain can appear in the right lower abdomen. The degree of pressure pain correlates with the extent of the lesion and is less responsive to pressure pain in the elderly. If the inflammation continues to worsen, the range of pressure pain will expand, and if appendiceal perforation has occurred, the patient’s pain and the range of pressure pain can spread to the whole abdomen; 2. Peritoneal stimulation signs: pressure pain, rebound pain and abdominal muscle tension in the abdomen are defensive reactions of the wall peritoneum stimulated by inflammation. Usually the presence of the above suggests that the inflammation of the appendix has increased, with pathological changes such as suppuration, gangrene or perforation. Extensive peritonitis indicates the presence of localized intra-abdominal exudate or perforation of the appendix. However, the signs of peritoneal irritation may not be obvious in children, the elderly, pregnant women, the obese, the frail, or in patients with posterior appendicitis of the appendix.