Gastric adenocarcinoma Ki67+30% generally indicates that the severity of the disease is not high, but clinical judgment of the severity of the disease needs to consider other influencing factors, and cannot rely on Ki67 alone. In order to determine the severity of gastric adenocarcinoma, apart from the Ki67 value, other factors such as the patient’s clinical stage and the differentiation degree of the adenocarcinoma should also be taken into account for comprehensive analysis. The value of Ki67 of gastric adenocarcinoma generally represents the proliferation of cancer cells, and the higher the value, the more malignant the cancer cells are and the more serious the disease is. The later the clinical stage of gastric adenocarcinoma is, the more serious the disease is. The lower the differentiation degree of adenocarcinoma cells, the higher the malignancy of adenocarcinoma, the more serious the disease is and the poorer the prognosis.