Lymph node fullness is a descriptive imaging term that generally means that the lymph nodes are enlarged. Lymph nodes are part of the body’s immune tissue structure and are generally oval in shape and are found in various parts of the body. Lymph node enlargement can be caused by a variety of causes, such as inflammation, tumors, and connective tissue diseases, and can result in a full lymph node pattern that resembles a round shape. If lymph nodes are found to be full on imaging, the patient should pay attention to it, and if necessary, further examination is recommended, including laboratory tests, other imaging tests, and pathologic tests. After the diagnosis is clear, the patient should be treated according to the cause of the disease. After the discovery of lymph node fullness, should improve the examination, clear diagnosis, do not delay the condition.