Nipple pain during menstruation is mostly due to physiological reasons, but it may also be due to breast hyperplasia, inflammation and other reasons, which require timely consultation. 1. Physiological factors: During menstruation, fluctuations in the level of progesterone and other sex hormones in the body can lead to physiological hyperplasia of the breast tissue to stimulate the nipple and lead to pain, which is not accompanied by localized fever and will be relieved after menstruation. 2. Pathological factors (1) Mammary hyperplasia: unilateral or bilateral pain can occur during menstruation, lumps can be touched in the painful area, and some of them also have nipple discharge during non-nursing period, etc. It is recommended to go to the hospital in time for consultation. (2) Inflammation of the mammary gland: in addition to pain, there may be redness, swelling, abnormal nipple secretion, enlarged lymph nodes and other manifestations. In addition, breast cancer, nipple eczema, mastitis and other diseases may also have similar symptoms, so it is recommended to go to the hospital in time when nipple pain occurs during menstruation.