Secondary prevention of coronary heart disease includes health education for patients and their families, targeted measures for atherosclerosis risk factors to prevent the progression of coronary artery lesions, drug or surgical prevention and treatment of myocardial ischemia, left ventricular insufficiency or severe arrhythmias, and minimization of susceptibility factors for those at high risk of reinfarction or sudden death. First, through good health promotion and education, make patients and their families aware of coronary heart disease and give active cooperation in the prevention and treatment of the disease. Prevent further development of coronary atherosclerotic lesions or promote their remission. 1.Reasonable dietary arrangement. Reasonable diet to reduce the total fat, saturated fat and cholesterol intake, overweight people should limit the total calories, if the blood lipid level is obviously abnormal, lipid regulators can be used. 2. Advise smokers to quit smoking. Smoking may induce coronary artery spasm, platelet aggregation, and reduce the reserve capacity of coronary artery and collateral circulation, which may aggravate coronary artery lesions and easily induce reinfarction. 3.Participate in physical activities and exercise. 4. Combined with hypertension or diabetes mellitus, it should be properly controlled. 3. Anti-platelet therapy. Platelets play an important role in the process of atherosclerosis formation, as well as in myocardial ischemia, myocardial infarction or sudden death caused by coronary artery spasm and thrombosis. Aspirin is an inexpensive and readily available antiplatelet agent with low side effects and easy long-term application, especially for men to prevent reinfarction. If aspirin is not available, Bolivar can be used as a substitute. Fourth, β-adrenergic blockers are currently considered effective drugs for secondary prevention after myocardial infarction. It can lower the heart rate and reduce myocardial oxygen consumption, prevent myocardial ischemia and sudden death. Fifth, calcium antagonists, the treatment of angina pectoris is effective, for hypertension and angina pectoris with calcium antagonists have certain benefits. The treatment of angina pectoris after myocardial infarction should be combined with the above-mentioned drugs in the near future after infarction, and coronary angiography should be done after the condition is stabilized, and coronary artery endovenous angioplasty or coronary artery bypass grafting should be selected according to the lesion. Seven, the prognosis of myocardial infarction combined with heart failure is poor. Further examination should be conducted to clarify the causes of heart failure so that treatment countermeasures can be considered. Patients with heart failure should use β-adrenergic blockers, ACEI or ARB drugs under the guidance of a doctor. Secondary prevention after myocardial infarction in coronary artery disease not only prolongs the life of patients, but also improves the quality of life and restores the ability to work. Therefore, secondary prevention should be actively promoted to every patient so as to effectively reduce the morbidity and mortality of coronary artery disease.