Gynecologic leukoplakia, also known as vulvar leukoplakia, develops on the vulva of women and manifests as limited or diffuse white patches. Vulvar leukoplakia has various causes, the most common of which are infection and inflammation of the vulva, in addition to endocrine disorders, genetic factors and so on. The main symptom of vulvar leukoplakia is vulvar itching, which is also the earliest symptom, and it is more serious at night, and it is often scratched due to unbearable itching, which then leads to infection and ulceration. The pathological manifestation of vulvar leukoplakia is squamous epithelial hyperplasia, which has certain cancerous possibility if not treated for a long time, so it should be treated actively. The main treatments for vulvar leukoplakia include medication, physical therapy, surgery, Chinese medicine and so on. Drug treatment mainly uses external drugs, such as dexamethasone cream, etc. If drug treatment is ineffective, physical therapy or surgery is needed, and attention should be paid to keep the vulva clean and dry. Although vulvar leukoplakia has the possibility of becoming cancerous, clinical treatment can cure most of the cases, so it is important to consult a doctor in time.