The recurrence of optic nerve myelitis is not only treated with hormone shock, but also with intravenous high-dose immunoglobulin and immunosuppressants. 1. Hormone shock: High-dose and short-course glucocorticoid shock is the most commonly used first-line treatment, which can inhibit inflammation and protect neurological function, such as the use of methylprednisolone, etc. Hormone shock has certain side effects, such as electrolyte disorders, upper and lower blood pressure. Hormones have certain side effects, such as electrolyte disorders, upper gastrointestinal bleeding, osteoporosis, femoral head necrosis, so we need to pay attention to potassium, calcium, acid-suppressing drugs and so on. 2. Intravenous high-dose immunoglobulin: For patients with poor response to hormones, high-dose immunoglobulin, such as gammaglobulin, can be used. 3. Use of immunosuppressants: for patients with obvious dependence on hormones and other autoimmune diseases, such as cyclophosphamide treatment. All of the above drugs should be used in accordance with medical advice. The recurrence of optic neuromyelitis optica is treated in a variety of ways, and prompt hospitalization is recommended.