The saturation and concentration of uric acid in the body at 37°C is about 420μmol/L (7mg/dl), above this concentration is hyperuricemia, and long-term hyperuricemia may lead to gout. Clinically, it is divided into primary hyperuricemia and secondary hyperuricemia, so its treatment includes the following aspects: primary hyperuricemia and gout treatment for lowering uric acid includes: 1. General treatment: control total dietary calories; limit alcohol consumption can be high purine food intake; drink a lot of water to increase the excretion of uric acid; carefully use drugs that inhibit uric acid excretion such as thiazide diuretics; avoid triggering factors and actively treat Related diseases. 2.Treatment of hyperuricemia: The aim is to maintain the normal level of uric acid. Mainly include: uric acid excreting drugs such as benzbromarone, drugs that inhibit uric acid production such as allopurinol, alkaline drugs such as sodium bicarbonate, new uric acid lowering drugs such as selective uric acid reabsorption inhibitors. 3. Treatment of acute gouty arthritis: After hyperuricemia develops into gout, colchicine, non-steroidal anti-inflammatory drugs and glucocorticoids are the first-line drugs for the treatment of acute gouty arthritis and should be used early. Management of interictal and chronic phases of gout attacks: For patients with frequent attacks of acute gouty arthritis, chronic gouty arthritis or gout stones, uric acid-lowering therapy should be performed. Treatment principles for secondary hyperuricemia: actively treat the primary disease; avoid or minimize the use of drugs and methods that may trigger and/or aggravate hyperuricemia; control the acute gouty arthritis attack as soon as possible. In addition, hyperuricemia and gout are often associated with metabolic syndrome, and should be actively treated with comprehensive treatment such as hypotension, lipid reduction, weight loss and improvement of insulin resistance. Therefore, the treatment of high uric acid should be based on the cause and condition of the patient, and the combination of medication and general treatment is necessary to achieve better results.