Facial aging is mainly due to the decrease of soft tissue volume, the decrease of skin elasticity and the atrophy of bone structure, of which volume loss is an important reason for the appearance of aging. Facial sagging is due to the redistribution of fat with age, localized fat atrophy or hypertrophy, and the facial contour changes from an “inverted triangle” to a “positive triangle”, losing the youthful upward and rounded curve. The best surgical solution for facial volume recovery and facial rejuvenation is now granular fat transplantation. In addition to the advantages of safe and non-rejection, easy to obtain, rich source, soft texture, real feel after injection, natural contouring, smooth and full contour and long-term maintenance, granular fat can also increase the collagen content in the skin and thicken the dermis under the action of fat stem cells, so that the luster of the facial skin, elasticity and suppleness can be significantly improved. At the same time, the rich blood circulation in the face can provide a better receptacle for the survival of fat cells, and the relatively small amount of fat grafting in the face is also conducive to the vascularization and viability of fat, which makes the fat grafting effect in improving the aging of the face and the contour of facial contouring more ideal. Facial Grid Zoning and Preoperative Aesthetic Evaluation The concept of facial rejuvenation of “holistic design and comprehensive aesthetics” is gaining popularity. In order to achieve the purpose of fine fat transplantation and maximize the natural and harmonious treatment effect of the face, preoperative aesthetic assessment is very important. With reference to facial aesthetic standards such as the three courts and five eyes, the golden section point, the curve of the facial arch, and the aesthetic plane, combined with the characteristics of autologous fat transplantation, we divide the whole face into 10 aesthetic units: forehead, eyebrows, nose, lips, chin, nasolabial folds, orbits, cheeks, ears, and so on. Temporal, ear, and then further subdivided into 49 aesthetic subunits according to the structural characteristics of each aesthetic unit, so that the facial aesthetics partitioning to form a grid. Facial aesthetics standards 1, facial front aesthetics standards (1) oval face is recognized as the world’s most beautiful face, head height and width of the ratio of the golden ratio of 1.618:1. (2) “three courts and five eyes”, the human face is highly symmetrical structure with the center line as the axis. (3) The width of the nose is 1/4 of the width of the face, and the width of the cleft of the mouth is 1/3 of the width of the face. (4) The eyelid fissure is slightly upward sloping, and the outer canthus is slightly higher than the inner canthus by 2-3mm. (5) The four facial arch curves: zygomatic arch line > eyebrow arch line > maxillary line > mandibular line. (2) Facial side aesthetic standards (1) ricketts plane: the facial side aesthetic plane, that is, the tip of the nose, the lower lip lip red and the point in front of the chin into a straight line. (2) The nose is the most three-dimensional organ of the face, and the standard aesthetic angles of the side are: nasal frontal angle of 120°~130°, nasal facial angle of 25°~30°, nasal tip angle of 10°~15°, and nasolabial angle of 90°~100°. 3. Aesthetic standard of facial centerline (1) Four highs: high forehead, high nasal tip, high lip pearl and high chin. (2) Three lows: low nasal root, low nasal base, low chin fossa. The face is divided into 10 aesthetic units: (1) forehead, (2) eyebrows, (3) nose, (4) lips, (5) chin, (6) nasolabial folds, (7) orbits, (8) cheeks, (9) temporal and (10) ears. 2, aesthetic subunits On the basis of 10 aesthetic units, it was subdivided into 49 aesthetic subunits. 1. The frontal region was divided into 5 aesthetic subunits, including the median frontal region, lateral frontal region, frontotemporal region, hairline region, and suprabrow region. The brow was divided into 4 aesthetic subunits, including the head, peak, tail, and inter-brow regions. 3. The nose was divided into 10 aesthetic subunits, including the root, upper dorsal, lower dorsal, mid-tip, upper tip, lower tip, lateral nose, soft triangle, nasal columella, and nasal wing areas. 4. The lip area was divided into 6 aesthetic subunits, including the upper red lip median zone (lip bead), upper red lip lateral zone, lower red lip median zone, lower red lip lateral zone, manubrium zone, and lip-nose lateral zone. 5. The chin region was divided into 4 aesthetic subunits, including the chin median, chin lateral, chin-lip groove, and chin base regions. 6, The nasolabial folds were divided into 4 aesthetic subunits from top to bottom according to Mendelson’s partitioning method, including: paranasal zone I, lateral upper lip zone II, lateral lower lip zone III, and lateral chin zone IV. 7, The orbital part was divided into 5 aesthetic subunits, including the brow lid area, the lid cheek area (tear trough area), the nasolabial area (medial canthus area), the blepharoplasty area, and the lower lid margin area (ocular table area). 8. The buccal region is the upper and lower buccal regions. The upper buccal region is defined as the area below the tear trough, above the base of the zygomatic bone, and between the nasolabial fold and the earlobe. The lower cheek area is the area below the base of the zygomatic bone, above the edge of the lower jaw, and between the outer corners of the mouth. There are 3 aesthetic subunits in the upper cheek area, including the upper cheek median area, the upper cheek medial area, and the lateral area; and there are also 3 aesthetic subunits in the lower cheek area, i.e., the lower cheek median area, the lower cheek medial area, and the lateral area. 9, The temporal part is 3 aesthetic subunits, including the superior temporal area, the middle temporal area and the inferior temporal area. 10. There are also 3 aesthetic subunits in the ear, namely, the supra-auricular, middle-auricular and infra-auricular regions (earlobes). Third, the method of preoperative aesthetic assessment and the significance of gridded aesthetic zoning 1. Methods First, the overall aesthetic assessment of the patient is performed, with reference to conditions such as age, personality, occupation, cultural cultivation, temperament, face shape, skin texture, and proportion of the five senses. Secondly, the patient was carefully observed in the standing position, lying position, and the different expressions of the face in action and at rest to analyze the specific position of the five senses, the overall contour morphology, the degree of aging, and the symmetry of the face and other aesthetic features. Then, by evaluating the specific shape of each aesthetic subunit of the 10 aesthetic units, combining the aesthetic assessment results of the four-dimensional aesthetic standards of points, surfaces, lines, and angles, the patient is carefully communicated with, and the subjective desires of the patient are fully taken into account to decide on the areas that need to be filled in, and the scope of the filler is drawn with methylene blue, and the key areas are marked with a rounded dot or “X” symbol, and the filler is then placed on the face according to the aesthetic characteristics of the patient. The key areas are marked with dots or “X” symbols, and the donor area is selected according to the estimated total amount of fat needed. 2.Significance Based on the overall facial aesthetic standard, the whole face was aesthetically zoned, and on this basis, in order to increase the operability of the clinic, the 10 aesthetic units were further gridded and zoned to form 49 aesthetic subunits. Emphasizing symmetry, harmony, naturalness, and youthfulness, the full-face granular fat injection treatment plan provides a reasonable aesthetic assessment and aesthetic reshaping of facial features and contours, and it can specifically target various areas of each patient to obtain a more ideal treatment result.