Acute lymphoblastic leukemia is also known as acute lymphoblastic leukemia, myeloid refers to acute myeloid leukemia, both are leukemias, there are low-risk, intermediate-risk and high-risk types, of which high-risk acute lymphoblastic and acute myeloid are more difficult to treat, and the treatment situation is related to the disease and the age of onset of the disease. 1. Both are malignant clonal proliferative lesions, acute myeloid leukemia is prevalent in children and young people, and may present with symptoms of enlarged liver and spleen lymph nodes or enlarged superficial lymph nodes, which are more likely to be relieved after induction chemotherapy but are also prone to relapse. Acute myeloid leukemia occurs in middle-aged and elderly people, and the main symptoms are anemia, infection and bleeding. 2. There are low-risk, intermediate-risk and high-risk types of these two kinds of leukemia, and its treatment effect is related to the patient’s age and disease, and it is not possible to judge which one is difficult to cure, and both of them need to be actively treated with medicines under the guidance of physicians, such as cyclophosphamide and vinblastine to be given to acute gonorrhea, and Zoerythromycin and Cytarabine to be given to the acute myeloid. After achieving complete remission, high-risk patients with acute lymphoma and acute myeloid who meet the indications for bone marrow transplantation are recommended to undergo allogeneic hematopoietic stem cell transplantation under the guidance of a physician in order to prolong the survival period.