Blisters on the vulva are usually associated with diseases such as genital herpes and eczema and are usually treated with medication. 1. Genital herpes: a sexually transmitted disease caused by the herpes simplex virus. Genital herpes is usually characterized by small blisters scattered or clustered in the genital and perianal areas, usually accompanied by pain. Oral antiviral drugs such as acyclovir and valacyclovir can be given, and topical acyclovir ointment and penciclovir cream can be used. 2. Eczema: It is a chronic, itchy skin disease with blisters, erythema, papules and other manifestations. Treatment is based on local treatment, can be used externally glucocorticoids such as hydrocortisone, tretinoin and other drugs. Vulvar blisters have many causes, it is recommended to consult a doctor in time to identify the cause, and then follow the doctor’s instructions for targeted treatment. Don’t use drugs indiscriminately, and keep clean and hygienic in daily life.