What are the complications of rheumatoid arthritis?

  Rheumatoid arthritis is a common systemic disease characterized by chronic inflammatory lesions of the joint tissue. The cause is unknown, and it occurs in various ethnic groups worldwide. The disease often affects multiple joints, mainly the small joints of the hands and feet, and is characterized by symmetric, persistent, progressive polyarthritis with progressive cartilage and bone destruction, resulting in joint deformity and loss of function. The main pathological changes are chronic inflammation of the synovial membrane, cellular infiltration, formation of synovial vascular opacities, infiltration of cartilage and bone tissue, resulting in structural damage to the joints, impaired function, and vasculitis, and extra-articular systemic manifestations, such as fever, anemia, subcutaneous nodules and lung damage, which are important causes of human labor loss and disability. The complications include: 1) joint deformities; 2) rheumatoid nodules; 3) vasculitis; 4) interstitial lung fibrosis; 5) digestive system: stomach pain, nausea, gastric bleeding; 6) coronary heart disease, myocarditis and pericarditis; 7) kidney damage; 8) peripheral neuropathy; 9) hematological system: anemia, thrombocytosis, etc.; 10) dry syndrome.