Stage III nephropathy, i.e. chronic kidney disease stage 3, requires the selection of appropriate therapeutic drugs according to the cause and condition. For example, oral ACEI or ARB drugs such as captopril, valsartan, etc. to reduce blood pressure, reduce urinary protein, alpha-keto acid tablets with a low protein diet to supplement nutrition, such as renal anemia can be oral iron such as ferrous succinate, etc., oral medicinal charcoal tablets to increase toxin elimination, and so on. Patients with chronic kidney disease stage 3 need to actively treat the primary disease, correct reversible factors, delay the progression of renal function, reduce cardiovascular risk, and treat anemia and other complications, so the specific medication needs to be based on the cause of the disease and the condition of the selection of the appropriate drugs. If timely and effective control of blood pressure, ACEI or ARB drugs such as captopril and valsartan can be preferred, which can not only lower blood pressure and reduce urinary protein, but also reduce myocardial remodeling and lower the incidence of cardiovascular events. Active hypoglycemic therapy, insulin can be applied, etc. Restrict protein diet, on the basis of low protein diet, can supplement the appropriate amount of alpha-keto acid tablets. In case of renal anemia and other complications, if it is iron deficiency anemia, oral iron agents such as ferrous succinate, ferrous sulfate, etc., and oral activated charcoal preparations such as medicinal charcoal tablets can be used to increase toxin elimination by intestinal route. All of the above medications should be used under the guidance of a doctor, avoid self-medication. Patients with chronic kidney disease (CKD) stage 3 are advised to go to regular hospitals in time and receive standardized treatment under the guidance of doctors.