The choice of open or minimally invasive surgery for pulmonary isolation needs to be determined by the patient’s specific condition. Minimally invasive surgery is usually the first choice for pulmonary isolation, and open surgery is only used if the patient’s condition is severe or if there is difficulty in evaluating minimally invasive surgery. 1. Minimally invasive surgery: also known as thoracoscopic surgery, with the help of the illumination and magnification of the thoracoscopic lens to remove the diseased lung tissue, this method is suitable for patients with pulmonary segregation of differentiation and heterogeneity of the tissue structure is relatively small. Minimally invasive surgery has the advantages of less trauma, less bleeding, faster postoperative recovery and shorter hospitalization time, which is the preferred surgical method for pulmonary isolation. 2. Open thoracic surgery: that is, to open the chest cavity to remove the diseased lung tissue, the surgery is more traumatic, suitable for patients with pulmonary isolation with differentiated heterogeneous tissue structure is relatively huge, the thoracic cavity is seriously adherent, or minimally invasive surgical operation is difficult. What kind of surgery should be used to treat pulmonary segregation disease needs to be evaluated by the doctor according to the actual situation of the patient, and the patient should actively cooperate with the doctor’s treatment.