Side effects of Criz, or lopinavir/ritonavir softgels, commonly include diarrhea and nausea, as well as headache, vomiting, and insomnia, which need to be taken care of. It is mostly used for the treatment of HIV/AIDS infections, or in combination with other antiretroviral drugs, and is mostly used for the treatment of HIV infections in children or adults older than 6 months of age. This medication is usually easy to tolerate and the most common side effects are diarrhea, nausea, weakness or fatigue, but also headache, vomiting and insomnia. In addition, increased aminotransferase activity, increased triglyceride levels, and hyperglycemia may occur. In clinical studies, about 1/4 of patients may have serious or fatal laboratory test abnormalities. Note that this product is contraindicated in persons who are hypersensitive to it; it should also be used with caution in persons with hepatic impairment. This product should be used in accordance with medical advice.