Quadrivalent HPV vaccine effective prevention for several years there is no exact time. There is no research and abundant clinical data to prove the specific time limit it can prevent, and it is found that it can have about 7 years of protection effectiveness after the first vaccination in foreign countries. Quadrivalent HPV vaccine can prevent HPV6, 11, 16 and 18 subtypes of the virus, there is no specific exact figure can answer the specific failure of its prevention of the virus, according to foreign clinical data, probably can be protected for at least 7 years. The efficacy of the vaccine also needs to vary from person to person, any vaccine does not have 100 percent preventive effect, ordinary life, women should pay attention to personal hygiene, regular review, cervical cancer and other regular screening. After receiving the quadrivalent HPV vaccine, if you have any questions, we recommend that you consult a professional doctor for answers.