Anluo pain tablets and diclofenac sodium extended-release tablets have not been found to have contraindications, generally can be used together, but should follow medical advice. Anluo pain tablets belongs to a kind of proprietary Chinese medicine, the drug can play a clinical role in activating the meridians and channels, activating blood to relieve pain (through the removal of blood stasis to relieve pain), the main target is the blockage of blood caused by the limbs and joints of pain and other symptoms. Sciatica, trigeminal neuralgia, rheumatic arthralgia, etc. belonging to this syndrome can be treated with this drug. The adverse reactions and contraindications of the drug are not clear. Diclofenac sodium extended-release tablets belong to the western medicine, has the effect of pain relief, in the clinic can also relieve the symptoms of rheumatoid arthritis, osteoarthritis and so on. The drug diclofenac sodium extended-release tablets may have side effects such as headache and dizziness. It is contraindicated in patients with a known allergy to the product, in patients who have induced asthma, hives or allergic reactions after taking aspirin or other non-steroidal anti-inflammatory drugs. The drug is contraindicated in the treatment of perioperative pain in coronary artery bypass grafting (CABG) surgery, in patients with a history of gastrointestinal bleeding or perforation following the application of NSAIDs, in patients with active peptic ulcers/bleeding, or who have had a recurrence of ulcers/bleeding in the past, and in patients with severe heart failure. In general, no contraindications to the use of the two drugs have been identified and they can be used together, but they should be administered under the supervision of a physician to avoid adverse effects.