Cough and runny nose can be seen in acute rhinitis, acute bronchitis, allergic rhinitis, etc., need to take the appropriate drugs according to the cause. 1. Acute rhinitis: commonly used drugs include decongestants and cough suppressants. Decongestants can relieve symptoms such as runny nose and nasal congestion, such as pseudoephedrine hydrochloride. If the cough symptoms are serious, cough suppressants can be applied, such as dextromethorphan. 2. Acute bronchitis: commonly used drugs include cough suppressants (e.g. codeine), antispasmodic and asthma drugs (e.g. aminophylline). If bacterial infection is present, antibiotics, such as penicillin, need to be applied. 3. Allergic rhinitis: commonly used drugs are antihistamines (such as cetirizine), glucocorticoids (such as prednisone acetate). It is recommended that patients actively seek medical attention, systematic examination to clarify the diagnosis and cause of the disease, under the guidance of the doctor to use drugs, do not self-medication.