After two years of chemotherapy, men can have children if their sperm are not abnormal. Chemotherapy drugs will have a certain effect on male sperm, can lead to less weak and abnormal spermatozoa, but not absolutely, there will still be a small portion of healthy sperm, and with the cessation of chemotherapy, sperm quality will gradually recover. Generally, half a year after the end of chemotherapy for semen routine and quality examination and analysis, there is a normal part of the sperm can be prepared for pregnancy, or choose assisted reproduction technology to select good quality embryos for transplantation to reduce the rate of fetal malformation. After pregnancy, you also need to do regular obstetrical examination and malformation screening to understand the development of the fetus.