Swelling of the upper eyelid without pain can be seen in healthy and normal people, but also in some diseases, such as nephritis and cardiovascular disease, etc., should be consulted in time to clarify the cause of the disease. 1. Physiological: Swelling of the upper eyelid may be caused by drinking a lot of water before going to bed, which is not a cause for concern and can be relieved by avoiding drinking a lot of water before going to bed. 2. Pathological: patients with nephritis not only have upper eyelid swelling, but also face and lower limbs, as well as dark tea-colored urine, increased foam in urine, high blood pressure, transient oliguria, fatigue and other symptoms. Cardiovascular disease causes upper eyelid edema is often accompanied by chest tightness, shortness of breath, dyspnea and other symptoms. If the upper eyelid edema symptoms can not be relieved by rest, it is recommended to go to the regular hospital as soon as possible, to clarify the specific causes, and comply with the doctor’s instructions, in order to avoid delaying the condition.