The aorta and the pulmonary artery, both of which have a certain pressure in the blood vessels, are known as blood pressure. Neonatal pulmonary hypertension means that after birth, the pressure in the pulmonary artery is higher than normal. If the pressure is higher than 25 mmHg, we consider that there is pulmonary hypertension. The most common cause of pulmonary hypertension in these patients is congenital heart disease, which may be combined with ventricular septal defect, atrial septal defect, or arterial ductus arteriosus. In these patients, because the pressure in the pulmonary artery is relatively high, the volume of blood is significantly increased, so cardiac ultrasound should be performed as soon as possible after birth. If elevated pulmonary artery pressures are seen in combination with several common congenital heart diseases, the patient should be advised to undergo early surgical treatment or medical interventional blockage to prevent further elevation of pulmonary artery pressures.