Rathke’s cyst is a pituitary cyst, a non-neoplastic lesion thought to be a remnant of Rathke’s capsule, located primarily in the pyriform plexus, with an autopsy incidence of 13%-23%. Adenopituitaries arise from the proliferation of cells in the anterior wall of the Rathke’s fissure, thus Rathke’s cyst and pituitary adenoma have a similar cellular origin and may, on rare occasions, coexist. On CT, it appears as an intracapsular space-occupying lesion without calcification or enhancement in the saddle, with or without suprasellar extension. Neurosurgery should be seen when this type of lesion occurs, with removal of the cyst as the primary if symptomatic. Some differential diagnoses are noted, mainly with other tumors such as craniopharyngiomas, which have a different treatment and prognosis.