Early childhood separation anxiety can be treated clinically with psychotherapy or medication: 1, psychotherapy, for parents, we should gradually cultivate children’s self-care ability, expand children’s contact with the world, train children to work together with others, communication and exchange, games, etc., in advance to prepare for the separation, for the children who have already had obvious separation anxiety, can be through relaxation training, biofeedback training, For children who already have obvious separation anxiety, relaxation training, biofeedback training, music therapy and other methods can be used to eliminate the symptoms of anxiety-induced muscle tension and vegetative nerve dysfunction; 2, drug treatment, for individual patients with more serious separation anxiety, affecting sleep, diet or the emergence of more serious physical symptoms, we can consider the application of anti-anxiety medication, mainly in the form of benzodiazepine drugs with a good therapeutic effect, such as diazepam, but also the use of β-blockers such as propranolol, and also the use of β-blockers, such as propranolol. Such as propranolol, can also achieve good therapeutic effect.