Calf tibialis anterior muscle pain may be caused by strenuous exercise, improper preparation before exercise and other physiological factors, generally do not need to take special treatment. Or it may be caused by muscle strain, pyriformis syndrome, etc. General measures, medication and physical therapy should be taken according to the cause. 1. Physiological factors: Strenuous exercise and improper preparation before exercise may cause repeated contraction of the tibialis anterior muscle, resulting in localized congestion and edema and muscle pain. This kind of situation, generally do not need to take special treatment, appropriate rest can be relieved. 2. muscle strain: tibialis anterior muscle pain in the calf may also be caused by muscle strain, patients need to rest, use ice packs within 72 hours of intermittent cold compresses, bandages on the strained area for bandages, the strained area elevated above the heart, can help reduce swelling. Or take aspirin, ketoprofen and other non-steroidal anti-inflammatory drugs under the guidance of a doctor to reduce secondary muscle damage. 3. Pear-shaped muscle syndrome: calf tibialis anterior muscle pain may also be caused by pear-shaped muscle syndrome, the patient can be under the guidance of the doctor for electrotherapy, ultrasound impact and other physical therapy to relieve the symptoms, but also follow the doctor’s instructions to take celecoxib, ibuprofen and other non-steroidal anti-inflammatory drugs. Patients with tibialis anterior muscle pain in the calf are advised to go to the hospital for standardized treatment under the guidance of a doctor.