Itchy and peeling skin on the palms of the feet can be considered to be caused by ringworm of the feet, contact dermatitis, palmoplantar keratosis, etc.; the treatment method is based on topical medications and internal medications. 1. Ringworm of the foot: the foot is infected by the fungus will appear peeling and itchy symptoms. Can be used externally antifungal drugs, such as ketoconazole cream, etc.; itching is serious, but also oral antihistamine drugs, such as loratadine, etc.; infection symptoms are more serious, oral antifungal drugs, such as itraconazole, terbinafine, etc.. 2. Contact dermatitis: when the feet come into contact with shoes, socks, cleaning agents and other allergens can cause skin allergies, resulting in the palms of the feet peeling and itching. It is necessary to use topical mometasone furoate cream and other glucocorticoid cream under the guidance of a doctor, oral cetirizine, loratadine and other antihistamine drugs. 3. Palmoplantar keratosis: It may be related to genetic factors, which will lead to different degrees of palmoplantar keratosis, and the palms of the feet will have peeling and itching. Under the guidance of the doctor, topical or oral retinoids can be used, or salicylic acid ointment can be used externally to soften the keratin and promote drug penetration. The cause of foot peeling and itching more reasons, it is recommended that patients go to a professional skin hospital, a clear diagnosis under the guidance of the doctor reasonable treatment, not blindly use their own medication.