Obese diabetes mostly belongs to type 2 diabetes and can be combined with other metabolic abnormalities such as hypertension, hyperlipidemia and hyperuric acid. Patients with obese diabetes are mostly accompanied by insulin resistance and can also be combined with insulin deficiency. The treatment of obese diabetes mainly includes the following points: 1. dietary treatment of diabetes, strict dietary control of diabetes, avoid high calorie, high fat, high carbohydrate diet, reduce the total calorie intake of one day, maintain the ideal weight as much as possible. 2. increase the amount of exercise, exercise can increase the total calorie consumption, which is conducive to weight control of obese patients, and can also improve insulin resistance and enhance insulin sensitivity 3, biguanide preparations, biguanide preparations can be used as the first choice of glucose-lowering drugs for obese diabetic patients, but also as a combination of oral hypoglycemic drugs, or combined with insulin therapy of the basic drug therapy. 4, enteroglucagon analogues (GLP-1 analogues): for example, Bactrim daily injection preparations, dullatanide weekly injection and so on series, both can Lowering sugar can also suppress excessive appetite, promote fat consumption and weight loss. 5, sodium-glucose co-transporter protein inhibitor (SGLT2 inhibitor), promote renal sugar and sodium excretion, lowering sugar at the same time can achieve weight loss lightly reduce blood pressure in hypertensive patients, reduce the heart and kidney burden with cardioprotective effect. When diet, exercise and the use of oral hypoglycemic drugs alone, can not make good control of blood sugar, can be combined with different mechanisms of drug therapy. At present, it is generally not recommended to add insulin as routine daily treatment for obese diabetes, and insulin therapy is only applied in stages when surgery and stress state.