Most antihypertensive drugs can affect sexual function to some extent, which is caused by the physiological effects of antihypertensive drugs. Under normal circumstances, blood pressure is regulated by the hypothalamic-renin-angiotensin system, and some antihypertensive drugs can act on this system to inhibit the effect, and at the same time, this system is inhibited will also affect the excitement of the sexual nerve, so that sexual function is weakened. Some diuretic antihypertensive drugs, such as spironolactone and hydrochlorothiazide, can also affect the secretion of sex hormones, which can reduce sex hormones and affect sexual function. For all the antihypertensive drugs, the use of which can prompt the body’s blood pressure to fall, which to a certain extent will affect the degree of erection of the penis, thus affecting male sexual function.