Liver-depression and spleen deficiency with upper heat and lower cold (upper heat and lower cold) needs to be treated after identification of the symptoms, and most of them are treated with proprietary Chinese medicines or oral soups, which can be used for liver-depression and spleen deficiency with Free Pill, and for upper heat and lower cold with Semixia Laxative Heart Soup. Liver Depression and Spleen Deficiency and Upper Heat and Lower Cold are two different diseases in Chinese medicine. Liver Depression and Spleen Deficiency refers to symptoms such as distension and pain in the chest and ribs, dizziness, loss of appetite, etc., which are caused by the liver’s lack of detachment (abnormal function of the liver’s detachment) and the spleen’s lack of healthy transportation, and are often treated with Easy Pills. Upper Heat and Lower Cold is a syndrome of mixed heat and cold (cold and heat symptoms occurring simultaneously in the same patient), causing the upper part of the body to manifest heat and the lower part to manifest cold, which can be regulated by Half Summer and Laxative Heart Soup, and together with Free Release Pill, it can be used to treat Liver Depression and Spleen Deficiency with Upper Heat and Lower Cold. When Liver Depression and Spleen Deficiency with Upper Heat and Lower Cold occurs, it is recommended to treat it after doctor’s guidance and identification to avoid delaying the condition.