The five hepatitis B tests are the most commonly used serum markers for testing hepatitis B virus infection in domestic hospitals, and their prices vary depending on the cost of the test method and the region in which they are located. There are five indicators of hepatitis B, namely hepatitis B surface antigen (HBsAg) and hepatitis B surface antibody (anti-HBs), hepatitis B e antigen (HBeAg) and hepatitis B e antibody (anti-HBe), and hepatitis B core antibody (anti-HBc), so we also call the five hepatitis B tests hepatitis B two-and-a-half. HBsAg is a sign of virus infection, but it does not reflect the presence or absence of virus replication, the degree of replication, or the weakness of infectiousness; HBsAb is a protective antibody, and a positive test means that the body has recovered or is resistant. HBcAb is a sign of previous infection or ongoing infection. The cost of hepatitis B five tests varies greatly depending on the manufacturer. The cost of domestic hepatitis B five tests is generally around 35-70 yuan, which is a qualitative test, showing only negative and positive results, and is often used in the usual medical checkups or primary screening tests for hepatitis B. The imported hepatitis B five tests cost more, generally around 240 yuan, and are quantitative tests that show the values of various indicators and can be used to assess the efficacy of hepatitis B antiviral treatment. Different hospitals may choose different tests, so the price varies. Doctors will also choose different methods depending on the needs of the patient. Therefore, the price of the five tests for hepatitis B varies depending on the test method, and the doctor will choose a different method according to the patient’s needs.