Intercostal neuralgia is a pain syndrome within the innervation zone of the intercostal nerves, primary is rare, but mostly secondary lesions, with causes such as thoracic diseases such as pleurisy, pneumonia and aortic aneurysm, trauma to the thoracic spine and ribs secondary to scab formation periostitis, tumors or malformations of the thoracic spine and ribs, tumors or inflammation of the thoracic medulla, etc. Herpes zoster intercostal neuralgia can be seen as a herpes in the corresponding intercostal space, and the pain can appear before the herpes and can still be present for a long time after it subsides. The pain can appear before the herpes and can persist for a considerable period of time after it subsides. Clinical manifestations of intercostal neuralgia: Pain can be located in one or several intercostal areas, is persistent, may increase paroxysmally, and may be aggravated by breathing, coughing and sneezing. Treatment of intercostal neuralgia: 1. causal treatment, such as removal of tumor, anti-infection, etc.; 2. symptomatic treatment, available analgesics and sedatives, etc.; 3. thoracic paravertebral nerve root closure, thoracic paravertebral sympathetic ganglion closure and intercostal nerve closure, etc. Examination of intercostal neuralgia: Intercostal neuralgia is generally diagnosed based on symptoms, and ordinary X-ray plain film is only useful for differential diagnosis. Secondary intercostal neuralgia requires chest X-ray, thoracic spine X-ray, lumbar puncture, etc. In addition, ultrasound and electrocardiogram are needed to exclude hepatobiliary, cardiovascular and pulmonary diseases.