Giant pustules on the skin may be caused by boils, carbuncles and other acute suppurative inflammation, which should be promptly treated with medication, surgery and physiotherapy under the guidance of a doctor. 1. Drug treatment: boils and carbuncles can be treated with ichthyol ointment or 50% magnesium sulfate wet compresses during the red and swollen stage, and penicillin or cephalosporin antibiotics, such as cefuroxime, amoxicillin and other antibiotics, can be taken orally for anti-infective treatments under the guidance of a doctor. 2. Surgical treatment: when there are pus spots or fluctuating sensation on the top of the boil, or when the carbuncle has appeared multiple pus spots, the surface is purple-brown, or the pus has broken, surgery should be taken in time for incision and drainage in order to discharge the pus and promote the recovery of the disease. 3. Physical therapy: mainly take ultra-short wave, infrared radiation and other physical therapy, for the relief of inflammatory reaction, pain and so on has a certain effect. Patients with giant skin pustules should go to the hospital in time and undergo appropriate treatment.