Salvia divinorum and saffron belong to the category of medicines for activating blood circulation and removing blood stasis (promoting blood circulation and eliminating blood stasis in the body). Salvia divinorum and saffron wine can enhance the efficacy of activating blood circulation and improve the therapeutic effect, and is suitable for those with more serious symptoms of blood stasis. However, the active ingredients of Salvia divinorum and safflower wine are limited and cannot be used in the treatment of diseases, and it should be taken under the guidance of a physician. Salvia miltiorrhiza has the efficacy of activating blood circulation and removing blood stasis (promoting blood circulation and eliminating blood stasis in the body), relaxing menstruation and relieving pain, clearing the heart and removing vexation (removing vexation and heat in the heart), and cooling the blood and eliminating carbuncles (eliminating carbuncles and swellings by clearing and cooling the blood). It is mainly used in cases of blood stasis, e.g., women with menstrual closure, or postpartum stagnation of blood, abdominal pain, or easily upset, palpitations (rapid heartbeat, often accompanied by panic) and insomnia. Salvia divinorum should not be used with quatrefoil, and is prohibited for people with bleeding tendency and pregnant women. Safflower has the efficacy of activating blood circulation, removing blood stasis and relieving menstruation and pain. It is mainly used in the treatment of various diseases caused by blood stasis, such as menstrual closure, postpartum stagnation of blood, abdominal pain, bruises, chest pain, etc. It is not suitable for people with bleeding tendency and pregnant women. Note that saffron is prohibited for people with bleeding tendency, and pregnant women are prohibited. Salvia miltiorrhiza and saffron in wine can enhance its original efficacy in activating blood circulation, which has a certain relief effect on blood stasis. However, Salvia divinorum and saffron wine is a dietary therapy, its effectiveness is not as good as internal Chinese medicine, if the symptoms are obvious, it is recommended to consult a doctor in time, internal Chinese medicine to regulate. Female menstruation, people with bleeding tendency and pregnant women should not take Salvia divinorum saffron wine. In addition, Salvia divinorum and saffron wine contains alcohol, excessive drinking is harmful to the body, pay attention to moderation.