Fever and headache occur in patients with acute sinusitis, often due to the obvious elevation of inflammatory cells and their own stress defense reaction, resulting in fever. Sometimes the patient’s body temperature often exceeds 38 degrees Celsius, and there is often a lot of secretion formation inside the sinuses, and the pressure in the sinus cavity will change, thus inducing the patient to have a headache. Sometimes it is pain at the arch of the eyebrow, sometimes the whole head is drowsy. In terms of treatment for aggressive anti-inflammatory and symptomatic management, cefixime capsules can be applied to reduce inflammation, and a clear history of allergy is required prior to the administration of the drug. The patient’s headache, can consider oral eucalyptus pin intestinal soft capsule to improve, can effectively promote the sinus cavity inside the secretion to the outside, after active treatment of the patient’s symptoms will gradually improve.