Squeeze syndrome is a condition in which soft tissues such as muscles are squeezed with force, resulting in swelling, bleeding, and necrosis in the local area. The absorption of toxins from necrotic tissues may cause serious damage to liver and kidney functions, especially kidney function, and acute renal failure and other serious problems. If the swelling is obvious and there is a lot of necrotic material, it is necessary to consider surgical incision and drainage for decompression. At the same time, the renal function is closely monitored. If it is obvious abnormalities in renal function, treatment such as dialysis needs to be chosen if necessary. Extrusion syndrome is very serious and there is a possibility of life threatening, especially with extensive extrusion. Then it is to strengthen nutritional support, anti-infection treatment, such as cephalosporin and other drugs, and closely observe the changes of local swelling.