The most common cause of white spots around the anus is the skin lesions caused by eczema around the anus. There are also some perianal diseases, such as hemorrhoids, anal fissures, anal fistulas, etc., which can cause long-term stimulation of the skin around the anus, resulting in the loss of skin pigment around the anus, thus leading to the formation of anal white spots. There is also a certain relationship with genetic factors, and it may also be a problem of the autoimmune system, a small number of anal leukoplakia patients will be accompanied by other immune system diseases. If the patient is caused by perianal eczema, perianal leukoplakia should be treated mainly for eczema, but all in all, the patient should go to the hospital in time to clarify the cause of the formation of white spots, and then the right treatment.