Involuntary twitching next to the nose is considered to be caused by facial muscle spasm. Facial muscle spasm refers to intermittent involuntary twitching of one side of the facial muscles, often due to facial nerve compression caused by vascular compression of the facial nerve is common, such as the posterior inferior cerebellar artery, vertebral arteries, and venous vascular compression, thus causing facial muscle spasm; secondly, the bridge cerebellar angle region of the sarcoidosis, tumors, and cysts such as compression of the facial nerve, can also be induced facial muscle spasm. The initial symptoms of facial muscle spasm patients mainly manifest as eyelid fluttering. As the condition worsens, it can lead to facial twitching, crooked mouth, tinnitus, facial muscle weakness and other symptoms, and can also cause involuntary twitching next to the nose. Once the phenomenon of involuntary twitching next to the nose occurs, it is necessary to go to the hospital in time for consultation and treatment to avoid the aggravation of the condition and the impact on health.