At present, the way to do the new coronavirus nucleic acid includes pharyngeal swab and nasopharyngeal swab. New coronavirus pneumonia is an acute infectious disease caused by new coronavirus infection, the way to do the new coronavirus nucleic acid test, whether it is a pharyngeal swab or a nasopharyngeal swab, is to extract the patient’s nasal or pharyngeal secretions to continue to carry out the subsequent testing, and finally determine whether there is a viral infection. Nucleic acid test is an important basis for the diagnosis of disease, but the results of clinical examination may be negative once, can not accurately rule out the disease, if necessary, need to be repeated several times to rule out the possibility of viral infection. It is recommended to avoid eating and drinking 2 hours before the nucleic acid test, and avoid drinking a lot of water and alcohol and smoking 30 minutes before the test, so as not to stimulate the nasal cavity or pharynx during the test, causing nausea and vomiting. Tip: “New coronavirus pneumonia and new coronavirus pneumonia” mentioned in this article were renamed to “new coronavirus infection” on December 26, 2022, as announced by the National Health Commission.